What Are PDO Mono Threads?
PDO Mono Threads are smooth, single-strand threads made of Polydioxanone (PDO), designed to stimulate collagen production and improve skin elasticity. Unlike barbed or cog threads, mono threads do not lift the skin mechanically but instead tighten, firm, and rejuvenate the skin by promoting natural collagen synthesis.

Scientific Mechanisms Behind PDO Mono Threads
🔬 How They Work: When inserted into the skin, PDO Mono Threads create a gentle tension, triggering a natural healing response that leads to collagen formation and skin tightening.
🔬 Collagen Production: The threads act as a scaffold, stimulating fibroblasts to produce more collagen, which helps improve skin firmness and elasticity.
🔬 Gradual Rejuvenation: Over 3-6 months, the threads dissolve, leaving behind newly-formed collagen that enhances skin texture and firmness.
Clinical Evidence Supporting PDO Mono Threads
A study titled "Periorbital Rejuvenation: A Study on the Use of Dermal Threads as Monotherapy" examined how PDO Mono Threads improve fine lines and skin laxity. The study involved 21 patients aged 40-65, each receiving 10 PDO Mono Threads in the periorbital region.
The results showed:
✅ Wrinkle Severity Reduced: Mean wrinkle score dropped from 2.29 to 1 post-treatment.
✅ High Patient Satisfaction: 16 out of 21 patients reported noticeable skin texture improvements.
✅ Minimal Side Effects: Mild bruising in two cases and thread displacement in one case within 24 hours.
💡 This study confirms that PDO Mono Threads effectively enhance skin texture and reduce fine lines with minimal downtime.
What Can PDO Mono Threads Treat?
✅ Fine lines & wrinkles – Smooths forehead, crow’s feet, and nasolabial folds.
✅ Loose skin – Firms areas such as the cheeks, jawline, and neck.
✅ Skin texture improvement – Enhances skin elasticity for a youthful glow.
✅ Acne scars & pores – Improves overall skin quality and smoothness.
✅ Décolletage & Hands – Can also be used on the neck, chest, and hands for rejuvenation.
💡 Looking for a PDO Mono Thread Lift in London? Our expert team at Hampstead Aesthetics specializes in advanced non-surgical facial rejuvenation.
How Do PDO Mono Threads Work?
PDO Mono Threads work by:
1️⃣ Triggering Collagen Production – The threads create a micro-inflammatory response, activating fibroblasts to produce new collagen.
2️⃣ Enhancing Skin Firmness – Over 3-6 months, the skin naturally tightens as collagen forms around the threads.
3️⃣ Gradual and Lasting Results – Even after the threads dissolve (within 6-12 months), collagen continues to improve skin texture and elasticity.
💡 Results from PDO Mono Threads are gradual and natural-looking, making them perfect for subtle skin rejuvenation.
How Long Do PDO Mono Threads Last?
⏳ Immediate Glow: Subtle firmness and a refreshed look appear within 2-3 weeks.
⏳ Peak Results: Best results are visible after 3 months, as collagen production increases.
⏳ Longevity: Effects last 9-12 months, depending on individual collagen response and skincare routine.
💡 Regular maintenance sessions (every 9-12 months) can prolong results.
PDO Mono Threads vs. Other PDO Thread Types
Feature | PDO Mono Threads | PDO Cog Threads | PDO Screw Threads |
Primary Purpose | Skin tightening & collagen stimulation | Lifting & firming | Volume restoration & symmetry |
Best For | Fine lines, mild skin laxity, texture | Sagging skin, jowls, deeper wrinkles | Volume loss, deep folds |
Downtime | Minimal (24-48 hours) | Slightly more (3-5 days) | Moderate (3-7 days) |
Longevity | 9-12 months | 12-18 months | 12-24 months |
Ideal Candidates | Younger patients, mild skin concerns | Moderate to severe sagging | Patients needing structural support |
💡 Not sure which PDO thread is best for you? Book a consultation with Dr. Chike at Hampstead Aesthetics to discuss your options.
Expert Insights from Dr. Chike Emeagi
"PDO Mono Threads are an excellent choice for those looking to refresh their skin naturally. They stimulate collagen production without adding volume, making them perfect for patients wanting skin tightening without fillers." – Dr. Chike Emeagi
About Dr. Chike
Under the expert care of Dr. Chike Emeagi MBBS, MRCGP, MRCS-Ed, MSc, MBA, a GMC-registered aesthetic doctor and Member of the Royal College of Surgeons of Edinburgh, you can expect safe and effective results tailored to your unique facial structure.
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